Code
APT-DPCX-01AX
Test
Active-Compendium
88342 x 1 or 88341 x 1
Clinical
Pathology
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered.
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Flag Active
True
Orderable Test Description
The gene DPC4 (deleted in pancreatic carcinoma 4, also called SMAD4) was identified in 18q21.3 This gene is frequently mutated and deleted in pancreatic carcinomas (55%) and less frequently (20 - 22%) in colon carcinomas. Loss of expression is specific for pancreatic malignancy (in-situ or invasive) vs. benign process, particularly helpful in biopsies.
Orderable Turn Around Time
1 Day
Keywords
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Immunohistochemistry (IHC)": {"Expression": ["DPC4"]}}
Keywords string
DPC4 expression, DPC4 IHC DPC4
Title URL
dpc4