Code
FSH-AMLS-03BX
Panel
Active-Compendium
88374x5 automated. If reflex is added, add 88374x5.
Clinical
Pathology
Bone Marrow Aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable.
Peripheral Blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable.
Fresh, Unfixed Tissue: Tissue in RPMI.
Bone Marrow/ Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 7 slides labeled with specimen type.
Fluids: Equal parts RPMI to specimen volume.
Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid.
Paraffin Block or Cut Slides: Not available.
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Peripheral Blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable.
Fresh, Unfixed Tissue: Tissue in RPMI.
Bone Marrow/ Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 7 slides labeled with specimen type.
Fluids: Equal parts RPMI to specimen volume.
Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid.
Paraffin Block or Cut Slides: Not available.
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Flag Active
True
Orderable Test Description
<p>Probes: CBFB inv(16), t(6;16) | KMT2A (MLL) (11q23) | PML/RARA t(15;17) | RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | RPN1, MECOM (3q21, 3q26.2)</p>
<p>Optional Reflex (available with Global cases only): 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | DEK/NUP214 (CAN) t(6;9) | p53 (17p13.1)/NF1 (17q11) | NUP98 (11p15) when the main panel is negative.</p>
<p>Probes may be ordered separately. Reflex results will be reported separately as AML Standard Reflex Panel.</p>
<p>Disease(s): Acute myeloid leukemia</p>
<p>Note: STAT processing is available by request for PML-RARA. Note STAT along with MD contact name and phone number to receive STAT results.</p>
<p>Optional Reflex (available with Global cases only): 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | DEK/NUP214 (CAN) t(6;9) | p53 (17p13.1)/NF1 (17q11) | NUP98 (11p15) when the main panel is negative.</p>
<p>Probes may be ordered separately. Reflex results will be reported separately as AML Standard Reflex Panel.</p>
<p>Disease(s): Acute myeloid leukemia</p>
<p>Note: STAT processing is available by request for PML-RARA. Note STAT along with MD contact name and phone number to receive STAT results.</p>
Orderable Turn Around Time
3-5 Days. STAT results for PML-RARA, when requested, are reported 12-24 hours from receipt in the NeoGenomics laboratory
Keywords
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["RUNX1T1/RUNX1 (ETO/AML1) t(8;21)", "PML/RARA t(15;17)"], "Structural Rearrangement(s)": ["MECOM", "KMT2A", "NUP98", "NUP214"], "Deletion(s)": ["5q-", "7q-"], "Inversion(s)": ["CBFB inv(16), t(16;16)"]}, "Deletion(s)": {"TP53 Deletion": ["TP53"]}}
Keywords string
AML, acute myeloid leukemia AML Standard FISH Panel
Title URL
aml-standard-fish-panel