ABL1 Kinase Domain Mutation Analysis

Submitted by Anonymous (not verified) on
Code
MOG-AKDX-01BV
Test
Active-Compendium
81170
Clinical
Oncology,Pathology
Peripheral blood: 5 mL in EDTA tube.
Bone marrow: 2 mL in EDTA tube.

Note: Test is RNA-based. Please select Extract & Hold - RNA if specimen hold service is desired.
Hematologic Diseases
Acute lymphoblastic leukemia (ALL)
Chronic myeloid leukemia (CML)
Molecular
Global
Flag Active
True
Orderable Test Description
RT-PCR and sequencing of the BCR-ABL1 fusion transcript for qualitative detection of mutations associated with resistance to Gleevec (imatinib) and other tyrosine kinase inhibitors. Analysis includes detection of all mutations recommended by guidelines, including the common T315I, Y253H, E255K/V, F359V/C/I, F317L/V/I/C, T315A, and V299L.
Orderable Turn Around Time
10 Days
Keywords
ABL1
BCR-ABL
BCR/ABL1
BCR-ABL1
Kinase Domain Mutation
T315I
Mutation Analysis
Meta Description
RT-PCR and sequencing of the BCR-ABL1 fusion transcript for qualitative detection of mutations associated with resistance to Gleevec (imatinib) and other tyrosine kinase inhibitors. Analysis includes detection of the common T315I mutation.

Hematologic disease
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection. Please select Extract & Hold - RNA if specimen hold service is desired.

Orderable Biomarkers
ABL1
NY Approved
True
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["ABL1"]}}
Keywords string
ABL1, BCR-ABL, BCR/ABL1, BCR-ABL1, Kinase Domain Mutation, T315I, Mutation Analysis ABL1 Kinase Domain Mutation Analysis
Title URL
abl1-kinase-domain-mutation-analysis