BRCA1/2 Mutation Analysis for Tumors | NeoGenomics Laboratories

Code

MOG-BMAP-03AX

Test

Active-Compendium

81163x1

Clinical

Oncology,Pathology

FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.

Mon, 01/13/2025 - 12:00

Wed, 01/22/2025 - 12:00

Next Generation Sequencing (NGS)

Global

Flag Active

True

Orderable Test Description

BRCA1 and BRCA2 mutation analysis is performed by next-generation sequencing of all coding exons of the BRCA1 and BRCA2 genes to detect point mutations and small insertions/deletions. This test does not detect large deletions or duplications.
This test is specifically for tumor specimens; please see our Hereditary Cancer Testing menu for germline (peripheral blood) testing requirements.

Orderable Turn Around Time

14 Days

Keywords

BRCA1

BRCA2

Meta Description

BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor.

Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers

BRCA2

BRCA1

NY Approved

True

Orderable Biomarkers JSON

{"DNA Sequencing": {"SNVs + Indels": ["BRCA2", "BRCA1"]}}

Keywords string

BRCA1, BRCA2 BRCA1/2 Mutation Analysis for Tumors

Title URL

brca1-2-mutation-analysis-for-tumors