JAK2 Exon 12-13 Mutation Analysis

Code
MOG-JAKX-01BX
Test
Active-Compendium
81279 (as of 01/01/2021); Prior to CPT Code was 81403
Clinical
Oncology,Pathology
Peripheral Blood: 5mL EDTA tube
Bone Marrow: 2mL EDTA tube
Note: Test is RNA-based. Please select Extract & Hold - RNA if specimen hold service is desired. If considering the MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL test as an add-on, we recommend adding Extract & Hold €“ DNA with Extract & Hold - RNA order.
Flag Active
True
Orderable Test Description
RT-PCR and bi-directional sequencing to detect mutations in exons 12-13, corresponding to the majority of the JAK2 pseudokinase domain. Exon deletion mutations are detectable. Testing is performed on plasma for increased sensitivity whenever possible. V617F analysis is recommended before or concurrently with this test. Exon 12-13 Mutation Analysis may be ordered separately, with concurrent V617F testing, by reflex after negative V617F testing, or as part of the MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL. Testing is approved for specimens from the state of New York.
Orderable Turn Around Time
7 Days
Medical Necessity Resources
/sites/default/files/2021-08/NeoTYPE-Myeloid-Panels-Medical-Necessity.pdf
Meta Description
RT-PCR and bi-directional sequencing to detect non-V617F mutations in exons 12-14, corresponding to the majority of the JAK2 pseudokinase domain. Exon deletion mutations are detectable. Testing is performed on plasma for increased sensitivity whenever possible.
Extra Note

NYS clients please provide date and time of Collection. Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Please select Extract & Hold - RNA if specimen hold service is desired.

Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["JAK2"]}}
Keywords string
jack 2, exon, exon 12 13, jak2 exon 12 13 JAK2 Exon 12-13 Mutation Analysis
Title URL
jak2-exon-12-13-mutation-analysis