JAK2 V617F Mutation Analysis - Quantitative

Code

MOG-JAQX-01BX

Test

Active-Compendium

81270 (x1)

Clinical

Oncology,Pathology

Bone Marrow Aspirate: 2-3 mL in EDTA tube (Preferred); Heparin (Acceptable)
Peripheral Blood: 3-5 mL in EDTA tube (Preferred); Heparin (Acceptable)
Note: Test is DNA-based. Please select Extract & Hold - DNA if specimen hold service is desired.

Hematologic Diseases

Myeloproliferative neoplasm (MPN)

Mon, 01/13/2025 - 12:00

Wed, 01/22/2025 - 12:00

Molecular

Global

Flag Active

True

Orderable Test Description

Quantitative detection of the V617F mutation, which is commonly found in myeloproliferative neoplasms (MPN). DNA is isolated and subjected to allele-specific polymerase chain reaction (PCR) amplification. Test report includes a bar graph to trend the mutational load.

Orderable Turn Around Time

7 Days

Keywords

JAK2 V617F

JAK2 MPN

Meta Description

<p>Quantitation of V617F is useful for monitoring MPN patients’ response to clinical treatment as V617F mutational load correlates with disease course, therefore can be used as a predictive marker.</p>

Extra Note

Please select extract & hold - DNA if specimen hold service is desired. Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers

JAK2

NY Approved

True

Orderable Biomarkers JSON

{"DNA Sequencing": {"SNVs + Indels": ["JAK2"]}}

Keywords string

JAK2 V617F, JAK2 MPN JAK2 V617F Mutation Analysis - Quantitative

Title URL

jak2-v617f-mutation-analysis-quantitative