MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL

Code
MOG-MPJB-03BZ
Test
Active-Compendium
81270, 81279, 81219, 81339 (as of 01/01/2021); Prior CPT Codes were 81270, 81403, 81219, 81402
Clinical
Oncology,Pathology
Peripheral blood: 5 mL in EDTA tube.
Bone marrow: 2 mL in EDTA tube.
Note: Test is RNA-based, NOT suitable for Freeze & Hold option.
Flag Active
True
Orderable Test Description
Sequential testing panel including qualitative detection of JAK2 V617F, JAK2 Exon 12-14, CALR exon 9, and MPL exon 10. Testing proceeds by reflex, with the next step triggered by a negative result or a weakly positive result of uncertain clinical significance; no further testing is performed once an informative result is obtained. Testing is performed on plasma for increased sensitivity whenever possible. Tests may also be ordered individually (see separate listing). Testing is approved for specimens from the state of New York.
Orderable Turn Around Time
7 to 10 Days
Medical Necessity Resources
/sites/default/files/2021-08/NeoTYPE-Myeloid-Panels-Medical-Necessity.pdf
Meta Description
Sequential testing panel including analysis of JAK2 V617F, JAK2 Exon 12-14, CALR exon 9, and MPL exon 10. Testing proceeds by reflex through the four-step panel until a mutation is identified, when the result is considered informative and no further testing is performed.
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["CALR", "MPL", "JAK2"]}}
Keywords string
mpn extended, mpn extended reflex, extended reflex, reflex panel, panel, myeloproliferative neoplasms, JAK2 V617F, JAK2, JAK2 Exon 12-14, CALR, calreticulin, MPL MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL
Title URL
mpn-jak2-v617f-with-sequential-reflex-to-jak2-exon-12-13-calr-and-mpl