Code
MOG-NMRX-01BZ
Test
Active-Compendium
81310
Clinical
Oncology,Pathology
Peripheral blood: 5 mL in EDTA tube.
Bone marrow: 2 mL in EDTA tube.
FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Note: Test is DNA-based. Please select Extract & Hold - DNA if specimen hold service is desired.
Bone marrow: 2 mL in EDTA tube.
FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Note: Test is DNA-based. Please select Extract & Hold - DNA if specimen hold service is desired.
Flag Active
True
Orderable Test Description
<p>NPM1 MRD Analysis is performed by PCR and fragment analysis of exon 12 of the NPM1 gene to detect small insertion mutations. Testing is performed on plasma with a PCR modification to improve sensitivity. The lower limit of detection of mutated NPM1 in this assay is 5 x 10^-3 (0.5%). Positive results are reported quantitatively if the percentage of mutated DNA is ≥1%, and they are reported qualitatively if ≥1%. </p>
Orderable Turn Around Time
7 Days
Keywords
Extra Note
Please select extract & hold - DNA if specimen hold service is desired. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
Orderable Biomarkers
NY Approved
False
Orderable Biomarkers JSON
{"Polymerase Chain Reaction (PCR)": {"SNVs + Indels": ["NPM1 (Exon 12)"]}}
Keywords string
Acute Myeloid Leukemia, Nucleophosmin NPM1 MRD Analysis
Title URL
npm1-mrd-analysis