Code
MOG-TRBX-01BZ
Test
Active-Compendium
81340
Clinical
Oncology,Pathology
Peripheral blood: 5 mL in EDTA tube.
Bone marrow: 2 mL in EDTA tube.
FFPE tissue: Paraffin block with at least 5mm2 of tissue size is preferred. Alternatively, send 1 H&E slide plus 4-5 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Fresh tissue: Two pieces minimum, 0.2 cm3 in RPMI. Note: not suitable for Freeze & Hold option.
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Note: Test is DNA-based. Please select Extract & Hold - DNA if specimen hold service is desired.
Bone marrow: 2 mL in EDTA tube.
FFPE tissue: Paraffin block with at least 5mm2 of tissue size is preferred. Alternatively, send 1 H&E slide plus 4-5 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Fresh tissue: Two pieces minimum, 0.2 cm3 in RPMI. Note: not suitable for Freeze & Hold option.
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Note: Test is DNA-based. Please select Extract & Hold - DNA if specimen hold service is desired.
Flag Active
True
Orderable Test Description
<p>This test provides qualitative detection of monoclonal T-cell receptor (TCR) beta gene rearrangements by PCR and fragment analysis according to BIOMED-2 consensus primer design. This test may be ordered concurrently with or after negative results in our T-Cell Receptor Gamma Gene Rearrangement assay for gamma gene rearrangements to improve TCR rearrangement detection by ~10% in T-cell leukemias/lymphomas.</p>
Orderable Turn Around Time
7 Days
Extra Note
Please select extract & hold - DNA if specimen hold service is desired. Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"FISH": {"Rearrangement(s)": ["TCR beta"]}}
Keywords string
This test provides qualitative detection of monoclonal T-cell receptor (TCR) beta gene rearrangements by PCR and fragment analysis according to BIOMED-2 consensus primer design. T-Cell Receptor Beta Gene Rearrangement
Title URL
t-cell-receptor-beta-gene-rearrangement