NEO AML Express | NeoGenomics Laboratories

Code

NTG-AMEP-02BX

Panel

Active-Compendium

Client-Bill Only

Clinical

Oncology,Pathology

Peripheral Blood: 2mL to 3mL in EDTA Tube. Bone Marrow Aspirate: 1mL to 2mL in EDTA Tube.

Mon, 01/13/2025 - 12:00

Wed, 02/12/2025 - 12:00

Next Generation Sequencing (NGS)

Global

Flag Active

True

Orderable Test Description

The NEO | AML Express assay is a next-generation sequencing (NGS) assay using combined DNA- and RNA-sequencing, which is used to identify prognostically and diagnostically informative alterations in acute myeloid leukemia (AML). The DNA sequencing component of this assay detects single nucleotide variants (SNVs) and indels in genes recurrently mutated in AML, and the RNA sequencing component detects fusions involving genes that are frequently involved in structural rearrangements observed in AML, as noted below. Test reports include a summary interpretation of all results together. 
DNA (38 genes): ABL1, ASXL1, BCOR, BRAF, CALR, CBL, CEBPA, CSF3R, DDX41, DNMT3A, ETV6, EZH2, FLT3 (ITD and TKD), GATA2, HRAS, IDH1, IDH2, JAK2, KIT, KRAS, MPL, NF1, NPM1, NRAS, PHF6, PPM1D, PRPF8, PTPN11, RUNX1, SETBP1, SF3B1, SRSF2, STAG2, TET2, TP53, U2AF1, WT1, ZRSR2 
RNA (9 genes): ABL1, KAT6A, KMT2A, MECOM, MYH11, NUP214, NUP98, RARA, RUNX1

Orderable Turn Around Time

5 Days

Keywords

AML NGS

AML diagnosis

acute myeloid leukemia NGS

acute myeloid leukemia diagnosis

rapid AML

rapid acute myeloid leukemia

AML

Meta Description

In conjunction with clinical features and other laboratory results, molecular profiling with the NEO Express AML panel may facilitate risk stratification and therapy selection for patients with newly diagnosed AML.

Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Important! To ensure fast TAT and sample stability, ship samples directly to NeoGenomics Houston.

Orderable Biomarkers

NY Approved

False

Orderable Biomarkers JSON

{"DNA Sequencing": {"SNVs + Indels": ["CSF3R", "DNMT3A", "ETV6", "EZH2", "CALR", "IDH1", "IDH2", "KIT", "HRAS", "KRAS", "NPM1", "NRAS", "PHF6", "PRPF8", "RUNX1", "SETBP1", "PTPN11", "SRSF2", "STAG2", "TET2", "U2AF1", "WT1", "SF3B1", "ZRSR2", "STK11", "DDX41", "MPL", "PPM1D", "NF1", "CBL", "ABL1", "CDKN2A", "FLT3", "JAK2", "GATA2", "PTEN", "TP53", "ASXL1", "BCOR", "BRAF", "CEBPA"]}, "RNA Sequencing": {"Fusions": ["KAT6A", "RARA", "MYH11", "ABL1", "KMT2A", "NUP98", "MECOM", "RUNX1", "NUP214"]}}

Keywords string

AML NGS, AML diagnosis, acute myeloid leukemia NGS, acute myeloid leukemia diagnosis, rapid AML, rapid acute myeloid leukemia, AML NEO AML Express

Title URL

neo-aml-express