Code
NTG-CCPX-02CX
Panel
Active-Compendium
81457x1, 88360x1, 88374x1 or 88377x1
Clinical
Oncology,Pathology
FFPE tissue: Paraffin block preferred. Please use 10% buffered formalin fixative. Do not use zinc fixatives.
Flag Active
True
Orderable Test Description
<p>The NeoTYPE Cholangiocarcinoma Profile analyzes 19 biomarkers through a combination of next-generation sequencing (NGS), FISH, and IHC as listed below. Test orders include summary interpretation of all results to help guide treatment decisions. A microsatellite instability (MSI) NGS result of "indeterminate" will create a reflex to MSI by PCR as long as the tumor percentage is ≥40% and paired normal tissue is available. NGS (15 genes + 2 biomarkers): APC, ARID1A, BAP1, BRAF, EGFR, ERBB2, HRAS, IDH1, IDH2, KRAS, MET (c-MET), NRAS, PBRM1, SMAD4, TP53, plus Microsatellite instability (MSI) and Tumor Mutation Burden (TMB). FISH (1 biomarker): FGFR2 IHC (1 biomarker): PD-L1 LDT.</p>
Orderable Turn Around Time
14 Days
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Structural Rearrangement(s)": ["FGFR2"]}, "DNA Sequencing": {"SNVs + Indels": ["HRAS", "IDH1", "IDH2", "KRAS", "NRAS", "ARID1A", "EGFR", "ERBB2", "MET", "SMAD4", "TP53", "APC", "BAP1", "BRAF", "PBRM1"], "Genomic Signatures": ["MSI", "TMB"]}, "Immunohistochemistry (IHC)": {"Expression": ["PD-L1"]}}
Keywords string
chollangio, cholangiocarcinoma, cholangio cancer, gene fusion NeoTYPE® Cholangiocarcinoma Profile
Title URL
neotype-cholangiocarcinoma-profile