NeoTYPE® Follicular Lymphoma Profile | NeoGenomics Laboratories

Code

NTG-FLPX-02CX

Panel

Active-Compendium

81450x1; 88374x3 or 88377x3

Clinical

Oncology,Pathology

FFPE tissue: Paraffin block. 10% NBF fixative is the recommended fixative. Do not use zinc or mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies.
Note: Test in TNA-based. Please select Extract & Hold - TNA if specimen hold service is desired.

Hematologic Diseases

Follicular lymphoma

Mon, 01/13/2025 - 12:00

Wed, 01/22/2025 - 12:00

Next Generation Sequencing (NGS)

Global

Flag Active

True

Orderable Test Description

<p>The NeoTYPE® Follicular Lymphoma Profile analyzes 16 genes through a combination of next-generation sequencing (NGS) and FISH as noted below. Test reports include a summary interpretation of all results together. FISH components may be ordered as "Tech-Only" by pathology clients who wish to perform the professional component. NGS (16 Genes): ARID1A, BCL2, BCL6, CDKN2A, CREBBP, EP300, EZH2, FAS, KMT2D, MAP2K1, MEF2B, PIK3CA, SOCS1, STAT6, TNFAIP3, and TNFRSF14For EZH2, the test can detect relevant mutations in Exons 16 and 18, including Y646N, Y646H, Y646F, Y646S, Y646C, A682G, and A692V. FISH probes: IgH/BCL2 t(14;18) | DUSP22-IRF4 (6p25.3) | TNFRSF14 (1p36).</p>

Orderable Turn Around Time

14 Days

Keywords

Meta Description

<p>The NeoTYPE® Follicular Lymphoma Profile has been developed to include a number of genes which are associated with lymphoma pathogenesis. Results from this test will aid in patient diagnosis, classification, prognosis, as well as treatment decisions.</p>

Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Please select Extract & Hold - TNA if specimen hold service is desired.

Orderable Biomarkers

NY Approved

False

Orderable Biomarkers JSON

{"DNA Sequencing": {"SNVs + Indels": ["BCL2", "EZH2", "KMT2D", "MAP2K1", "MEF2B", "BCL6", "CREBBP", "CDKN2A", "EP300", "ARID1A", "FAS", "SOCS1", "STAT6", "TNFAIP3", "TNFRSF14", "PIK3CA"]}, "Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["DUSP22-IRF4", "t(14;18)", "TNFRSF14"]}}

Keywords string

Lymphoma, Follicular Lymphoma, B-Cell Lymphoma, B Cell NeoTYPE® Follicular Lymphoma Profile

Title URL

neotype-follicular-lymphoma-profile