NeoTYPE® GIST and Soft Tissue Tumor Profile

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Code
NTG-GSTX-02CX
Panel
Active-Compendium
81457x1, 88377x2, 88360x1
81479
Clinical
Oncology,Pathology
FFPE tissue: Paraffin block preferred. Please use 10% buffered formalin fixative. Do not use zinc fixatives.
Next Generation Sequencing (NGS)
Global
Flag Active
True
Orderable Test Description
<p>The NeoTYPE GIST/Soft Tissue Tumor Profile analyzes 43 biomarkers through a combination of next-generation sequencing (NGS), FISH, and IHC as listed below. Test orders include summary interpretation of all results to help guide treatment decisions. A microsatellite instability (MSI) NGS result of "indeterminate" will create a reflex to MSI by PCR as long as the tumor percentage is &ge;40% and paired normal tissue is available. NGS (38 genes + 2 biomarkers): AKT1, AKT2, AKT3, ARID1A, ATM, BRAF, CDKN2A, CTNNB1, ERBB2, ERBB4, FGFR1, FGFR2, FGFR3, GNAS, HRAS, KIT, KRAS, MAP2K1, MET, Microsatellite Instability (MSI), NF1, NRAS, NTRK1 fusions, NTRK2 fusions, NTRK3 fusions, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, SDHA, SDHB, SDHC, SDHD, SMAD4, SMO, SRC, TERT Promoter, TP53, Tumor Mutation Burden (TMB) FISH (2 FISH): MET, PTEN (tech-only available) IHC (1 biomarker): PD-L1 LDT (tech-only available).</p>
Orderable Turn Around Time
14 Days
Keywords
precision profile
solid tumors
neo type
NeoTYPE Precision Profile for Solid Tumors.
Meta Description
The NeoTYPE Thyroid Profile is useful to classify fine needle aspirates of thyroid nodules that are indeterminate or suspicious on cytology.
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers
PTEN
MET
PD-L1
MSI
TMB
HRAS
KIT
KRAS
NRAS
PTPN11
MAP2K1
AKT2
AKT3
NF1
RB1
CDKN2A
TERT
SDHA
SDHB
SDHC
SDHD
AKT1
ARID1A
ATM
FGFR2
FGFR3
CTNNB1
ERBB2
ERBB4
NTRK1
FGFR1
NTRK2
MET
SMO
NTRK3
PDGFRA
PIK3CA
GNAS
PTEN
SMAD4
TP53
SRC
BRAF
NY Approved
True
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["HRAS", "KIT", "KRAS", "NRAS", "PTPN11", "MAP2K1", "AKT2", "AKT3", "NF1", "RB1", "CDKN2A", "TERT", "SDHA", "SDHB", "SDHC", "SDHD", "AKT1", "ARID1A", "ATM", "FGFR2", "FGFR3", "CTNNB1", "ERBB2", "ERBB4", "NTRK1", "FGFR1", "NTRK2", "MET", "SMO", "NTRK3", "PDGFRA", "PIK3CA", "GNAS", "PTEN", "SMAD4", "TP53", "SRC", "BRAF"], "Genomic Signatures": ["MSI", "TMB"]}, "Immunohistochemistry (IHC)": {"Expression": ["PD-L1"]}, "Fluorescence In Situ Hybridization (FISH)": {"Amplification(s)": ["MET"], "Deletion(s)": ["PTEN"]}}
Keywords string
precision profile, solid tumors, neo type, NeoTYPE Precision Profile for Solid Tumors. NeoTYPE® GIST and Soft Tissue Tumor Profile
Title URL
neotype-gist-and-soft-tissue-tumor-profile