Code
NTG-LDPX-02CX
Panel
Active-Compendium
81455x1
81450x1
Clinical
Oncology,Pathology
Bone Marrow Aspirate: 2-3 mL in EDTA tube
Peripheral Blood: 3-5 mL in EDTA tube
FFPE tissue: Paraffin block. Alternatively, send 1 H&E slide plus 10-14 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative is the recommended fixative. Do not use zinc or mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies.
Note: Test in TNA-based. Please select Extract & Hold - TNA if specimen hold service is desired.
Peripheral Blood: 3-5 mL in EDTA tube
FFPE tissue: Paraffin block. Alternatively, send 1 H&E slide plus 10-14 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative is the recommended fixative. Do not use zinc or mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies.
Note: Test in TNA-based. Please select Extract & Hold - TNA if specimen hold service is desired.
Flag Active
True
Orderable Test Description
The NeoTYPE Lymphoid Disorders Profile detects DNA mutations (SNVs and InDels) in 128 genes across multiple lymphoma/leukemia subtypes through next-generation sequencing (NGS): ABL1, ABL2, ALK, ARHGEF1, ARID1A, ARID2, ASXL1, ATM, B2M, BCL2, BCL6, BCOR, BIRC3, BRAF, BTK, CARD11, CCND1, CCND2, CCND3, CD274, CD79A, CD79B, CDKN1B, CDKN2A, CDKN2B, CIITA, CREBBP, CRLF2, CSF1R, CTCF, CTNNB1, CXCR4, DDX3X, DIS3, DNMT3A, EBF1, EGR1, EP300, EPOR, ETV6, EZH2, FAM46C, FAS, FAT1, FBXW7, FGFR3, FOXO1, GATA3, GNA13, GNAI2, HIST1H1E, HRAS, ID3, IDH1, IDH2, IKBKB, IKZF1, IKZF3, IRAK4, ITPKB, JAK1, JAK2, JAK3, KLF2, KMT2D, KRAS, MALT1, MAP2K1, MAP3K14, MAPK1, MED12, MEF2B, MYC, MYCN, MYD88, NF1, NFKBIE, NOTCH1, NOTCH2, NOTCH3, NRAS, NT5C2, P2RY8, PDGFRB, PHF6, PIK3CA, PIK3CD, PIK3R1, PIM1, PLCG1, PLCG2, POT1, PPM1D, PRDM1, PRPS1, PTEN, PTPN11, RB1, REL, RHOA, RIPK1, RPS15, RUNX1, S1PR2, SAMHD1, SETD2, SF3B1, SGK1, SH2B3, SOCS1, SPEN, STAT3, STAT5B, STAT6, TBL1XR1, TCF3, TET2, TLR2, TNFAIP3, TNFRSF14, TP53, TRAF2, TRAF3, UBR5, WT1, XPO1, ZFHX4, and ZMYM3. Test reports include a summary of all results together.
Orderable Turn Around Time
14 Days
Keywords
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection. Please select Extract & Hold - TNA if specimen hold service is desired.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["KMT2D", "MAP2K1", "PIK3CD", "PIM1", "MED12", "MEF2B", "MYC", "PPM1D", "MYCN", "NF1", "NOTCH2", "NOTCH3", "PIK3R1", "PRDM1", "REL", "RHOA", "RB1", "SETD2", "SOCS1", "SPEN", "STAT3", "STAT5B", "TNFAIP3", "TNFRSF14", "TCF3", "XPO1", "TRAF2", "ARHGEF1", "CIITA", "DDX3X", "EBF1", "ABL1", "EGR1", "ABL2", "CDKN2A", "CRLF2", "CSF1R", "EPOR", "FGFR3", "GNAI2", "IKZF1", "STAT6", "JAK1", "H1-4", "JAK2", "IKBKB", "JAK3", "IKZF3", "IRAK4", "ITPKB", "KLF2", "PDGFRB", "SH2B3", "B2M", "NFKBIE", "TP53", "ASXL1", "BCOR", "NT5C2", "BRAF", "P2RY8", "DNMT3A", "ETV6", "EZH2", "HRAS", "IDH1", "IDH2", "PLCG1", "POT1", "KRAS", "NRAS", "PHF6", "PTPN11", "RUNX1", "PRPS1", "SF3B1", "TET2", "WT1", "RIPK1", "RPS15", "S1PR2", "SAMHD1", "SGK1", "TBL1XR1", "TLR2", "TRAF3", "DIS3", "UBR5", "ZFHX4", "ZMYM3", "ARID1A", "ATM", "CTNNB1", "GATA3", "PIK3CA", "PTEN", "FOXO1", "BCL2", "BIRC3", "BTK", "CARD11", "CD79B", "CXCR4", "MYD88", "NOTCH1", "PLCG2", "FBXW7", "ALK", "ARID2", "ID3", "BCL6", "CCND1", "CCND2", "CCND3", "CD274", "CD79A", "CDKN1B", "CDKN2B", "CREBBP", "CTCF", "MALT1", "MAP3K14", "MAPK1", "EP300", "TENT5C", "FAS", "FAT1", "GNA13"]}}
Keywords string
Heme Cancers, Hematologic Disorders, Hematologic Malignancies, Lymphoid Disorders, lymphoma, leukemia NeoTYPE® Lymphoid Disorders Profile
Title URL
neotype-lymphoid-disorders-profile