Code
NTG-MDSX-02CX
Panel
Active-Compendium
81450x1
81450
Clinical
Oncology,Pathology
Bone marrow (Preferred): 2 mL in EDTA tube.
Peripheral blood: 5 mL in EDTA tube.
FFPE tissue: Paraffin block. Alternatively, send 1 H&E slide plus 10-14 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative is the recommended fixative. Do not use zinc or mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies.
Note: Test in TNA-based. Please select Extract & Hold - TNA if specimen hold service is desired.
Peripheral blood: 5 mL in EDTA tube.
FFPE tissue: Paraffin block. Alternatively, send 1 H&E slide plus 10-14 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative is the recommended fixative. Do not use zinc or mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies.
Note: Test in TNA-based. Please select Extract & Hold - TNA if specimen hold service is desired.
Flag Active
True
Orderable Test Description
<p>This test is performed by sequencing the entire coding regions of the genes listed unless another method is noted.</p>
<p>ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CEBPA, CSF3R, CUX1, DDX41, DNMT3A, ETNK1, ETV6, EZH2, FLT3, GATA2, GNB1, HRAS, IDH1, IDH2, JAK2, KIT, KRAS, MPL, NF1, NPM1, NRAS, PDGFRA, PHF6, PIGA, PPM1D, PTEN, PTPN11, RUNX1, SETBP1, SF3B1, SRSF2, STAG2, STAT3, STAT5B, TET2, TP53, U2AF1, WT1, and ZRSR2. </p>
<p>Note: FLT3 by PCR (via FLT3 Mutation Analysis) is available to be ordered, as Client-Bill only, in conjunction with the NeoTYPE MDS/CMML Profile. It is reported separately from the NeoTYPE Profile for the purpose of prompt therapy selection in patients with a new diagnosis of AML.</p>
<p>ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CEBPA, CSF3R, CUX1, DDX41, DNMT3A, ETNK1, ETV6, EZH2, FLT3, GATA2, GNB1, HRAS, IDH1, IDH2, JAK2, KIT, KRAS, MPL, NF1, NPM1, NRAS, PDGFRA, PHF6, PIGA, PPM1D, PTEN, PTPN11, RUNX1, SETBP1, SF3B1, SRSF2, STAG2, STAT3, STAT5B, TET2, TP53, U2AF1, WT1, and ZRSR2. </p>
<p>Note: FLT3 by PCR (via FLT3 Mutation Analysis) is available to be ordered, as Client-Bill only, in conjunction with the NeoTYPE MDS/CMML Profile. It is reported separately from the NeoTYPE Profile for the purpose of prompt therapy selection in patients with a new diagnosis of AML.</p>
Orderable Turn Around Time
14 Days
Keywords
Medical Necessity Resources
/sites/default/files/2021-08/NeoTYPE-Myeloid-Panels-Medical-Necessity.pdf
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection. Please select Extract & Hold - TNA if specimen hold service is desired.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["CSF3R", "DNMT3A", "ETV6", "EZH2", "HRAS", "CALR", "IDH2", "KIT", "IDH1", "KRAS", "NPM1", "NRAS", "PHF6", "PIGA", "PTPN11", "RUNX1", "SETBP1", "SF3B1", "SRSF2", "STAG2", "TET2", "U2AF1", "WT1", "ZRSR2", "DDX41", "MPL", "PPM1D", "NF1", "BCORL1", "CBL", "CUX1", "ETNK1", "FLT3", "GNB1", "STAT3", "JAK2", "STAT5B", "GATA2", "PDGFRA", "PTEN", "TP53", "ASXL1", "BCOR", "BRAF", "CEBPA"]}}
Keywords string
mds, cmml, neo type, neotype, NeoTYPE MDS/CMML Profile NeoTYPE® MDS/CMML Profile
Title URL
neotype-mds-cmml-profile