RAS/RAF Panel

Code
NTG-RRPX-02AX
Panel
Active-Compendium
81404 - HRAS, 81405 - KRAS, 81406 - BRAF, 81479 - NRAS
81479
Clinical
Oncology,Pathology
FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Flag Active
True
Orderable Test Description
The RAS/RAF Panel is an NGS-based assay performed by sequencing the entire coding region (full gene) of BRAF, HRAS, KRAS and NRAS genes. The panel reports mutations detected in the full gene including mutations in the most common hotspots, if present. The common hotspots include KRAS (exons 2-4, including codons 12, 13, 59, 61, 117, and 146), NRAS (exons 2-4, including codons 12, 13, 59, 61, 117, and 146), HRAS (exons 2-3, including codons 12, 13, 59, and 61), and BRAF (exons 11, 15 including codon V600).
Orderable Turn Around Time
10-14 Days
Meta Description
The RAS/RAF Panel is concurrent sequence analysis of four genes with a single report: KRAS (exons 2-4), NRAS (exons 2-4), HRAS (exons 2-3), and BRAF (exons 11 and 15). KRAS and NRAS codons analyzed include 12, 13, 59, 61, 117, and 146.
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"RNA Sequencing": {"Fusions": ["HRAS", "NRAS", "KRAS", "BRAF"]}}
Keywords string
KRAS, NRAS, BRAF, HRAS, ras raf, ras-raf, codon 12, colorectal, raf RAS/RAF Panel
Title URL
ras-raf-panel